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#1 TESTOSTERONE BOOSTER AS VOTED FOR BY READERS OF PULSE MAGAZINE!

COMPLETE TESTOSTERONE SUPPORT*

TESTOSTERONE…

It builds men. But you don’t want to let your own physical limitations hold you back! What you need is an equalizer. You want Activate Xtreme™!

Do you want to bust through plateaus, set new personal records and get bigger?*

If you answered “yes” to any of these, then welcome to the world fuelled by Activate Xtreme™. For years supplement companies have been churning out products promoted as testosterone boosters with large marketing budgets and flashy graphics in order to drill home to the masses that the product is brilliant. While some of these formulas may have been mildly effective, the vast majority of these companies used loose theories and spent more on the advertising than on research and development.

Using compounds with NO SCIENTIFIC BACKING just doesn’t cut it.

To complicate things further, many companies went out of their way to re-hash the old ideas of the more innovative companies, or simply ripped off their newest ideas as quickly as possible. To put it plainly, those who can, do, and those who can’t, copy.

Activate Xtreme™ stands apart from its competitors that have ceaselessly attempted to copy the design, but have never quite bettered or even matched it.

The researchers at DS spent several years researching and developing the formula that would go on to become what we feel is the INDUSTRY STANDARD for healthy, natural testosterone support.

What resulted was a product so effective that it has been at the top of its game FOR YEARS. Activate Xtreme™ just might change your life! Here’s why:

The SCIENCE behind Activate Xtreme™ REVEALED

Activate Xtreme™ is designed around Divanil®, a compound tried, tested and scientifically researched to help enhance free testosterone by binding to sex-hormone binding globulin (SHBG).* SHBG is the core controller of your FREE TESTOSTERONE. When SHBG binds testosterone it can no longer promote muscle mass. In other words, SHBG TURNS TESTOSTERONE OFF!

Divanil® works to prevent this effect from occurring, providing support to help ensure that YOUR testosterone stays SWITCHED ON.*

But Activate Xtreme™ does not only cater for free testosterone.

Testosterone and Growth Hormone

Mucuna pruriens is an adaptogenic herb mostly found in hot climates like India and Africa. While the antioxidant and neuro-protective qualities it possesses are of benefit for a healthy body and mind, it is the effects it exerts on the endocrine system that make it such a great compound.*

Luteinizing hormone (LH) is a hormone produced by the pituitary gland of the brain. Upon its release it stimulates cells found in the testicles called Leydig cells to synthesize testosterone. Mucuna pruriens increases levels of LH, which may help support increases in testosterone.* Research has suggested that mucuna pruriens contains several alkaloids, but the main constituent responsible for this effect is L-Dopa. L-Dopa is a direct precursor for dopamine, which regulates the sex hormones control center in the brain.

Mucuna pruriens has also been suggested to promote elevated levels of growth hormone (GH) in the body. This is interesting because GH is involved heavily in sex hormone synthesis, in particular by regulating something called Steroidogenic acute regulatory protein (stAR). stAR is a transport protein found in Leydig cells that controls cholesterol uptake by the mitochondria in these cells. Why is this important? Because this is the rate-limiting step in testosterone synthesis.

So not only does mucuna pruriens work to help boost testosterone via LH stimulation, it may help support the machinery required to synthesize it through GH augmentation.* But that is not all!

Mucuna pruriens has been known for centuries as an aphrodisiac and to help support a healthy libido.* It has been suggested that this is due to its effect reducing prolactin.* Prolactin is a hormone primarily associated with lactation in women who breastfeed, however in men it is released after orgasm, resulting in loss of erection and a short-term reduction of sexual appetite. This is called the refractory period and can last anywhere from seconds in young men, to thirty or more minutes in older men. Dopamine inhibits prolactin release, leading to a reduced refractory period. By boosting dopamine levels, it has been suggested that mucuna pruriens may help enhance your sexual experience!

Other research has also surmised that mucuna pruriens reduces stress in humans.* In fact, blood testing has indicated that mucuna pruriens may reduce the chief stress hormone, cortisol.

Something of interest, however, is that studies have been carried out investigating whether there is a difference to taking a mucuna pruriens extract containing L-Dopa, and taking synthetic L-Dopa. Amazingly it appears that the other alkaloids found in mucuna pruriens make the L-Dopa content more orally bioavailable than taking the synthetic version alone!* This is why Activate Xtreme™ contains both a high-potency 95% extract of L-Dopa along with a lower 20% mucuna pruriens extract!

MORE testosterone

Tongkat ali is an herb primarily found in South East Asia, where it is traditionally believed to enhance the sexual voracity of men.* Studies involving rodents appear to back up this belief, and human trials do seem to show some promise, particularly for improving stress, and boosting sex hormones.* It is theorized that the latter is achieved by lowering SHBG, much like Divanil®.

Activate Xtreme™ additionally contains an herb called pedalium murex, which has been used traditionally in India where it is believed to have aphrodisiac qualities.* This belief appears to have some merit, after a recent rodent study indicated that pedalium may possess some aphrodisiac qualities as a rejuvenative tonic.* This same study also demonstrated a sizeable increase in testosterone in the rodents – an effect that persisted for several days even after cessation of the extract.*

But wait, there’s more!

Activate Xtreme™ does not stop at supporting increased total and free testosterone.*

Classified as an adaptogen like mucuna pruriens by herbalists, rhodiola rosea has become one of the most popular choices of adaptogen in recent years for good reason, as it is believed to exert a number of benefits via several different biochemical pathways.* Adaptogens are believed to possess the ability to balance the endocrine and immune systems, helping the body maintain homeostasis, while amazingly achieving this effect without negative effect on other biological systems.*

Bodybuilders and athletes may benefit greatly from rhodiola rosea due to its potential effect on improving endurance performance and assisting with recovery after exercise.* The purported mechanism of these great benefits appears to be by increasing ATP production within the mitochondria of muscle cells thus increasing the energy “currency” of the cell that drives recuperative processes such as protein synthesis.*

Rhodiola may also have neural-cognitive effects, such as reducing mental fatigue and acting somewhat as a nootropic or “smart herb”.* These neural effects also appear to manifest in other ways, such as improved mood, possibly due to rhodiola being an inhibitor of an enzyme called catechol-O-methyl-transferase (COMT).*

Cholecalciferol (Vitamin D3) for total testosterone support*

Cholecalciferol is also known as vitamin D3. Notice that it is not generic “vitamin D”. This distinction is important because vitamin D is not a single compound like you may think. Much like the B vitamins, it is actually a group of several compounds. Medical breakthroughs over the decades have occurred at varying rates and so D3 was grouped with other compounds as a single entity under “vitamin D”. New research has shed light on the other entities within the group and their roles in biochemistry have been elucidated. And the research into D3 is quite incredible.

Cholecalciferol is in fact a hormone precursor for the active form of D3 in the body, called calcitriol (1,25-hydroxy vitamin D3).* While some D3 can be obtained from dietary intake such as fish, cheese or fortified milk, the majority of D3 is derived from the sun. Ultraviolet light from the sun reacts in the skin with a type of cholesterol, called 7-hydrocholesterol, to form D3. D3 is then converted to 25-hydroxy vitamin D3 (calcidiol) in the liver, which is then passed to the kidney where it becomes 1,25-hydroxy vitamin D3 (calcitriol).

Most people do not get enough D3, namely because they do not eat a balanced diet, nor do they get outside as much as they should. Combine this with the darker winter months that a lot of people endure, D3 deficiency has been identified as a legitimate concern. This is because D3 plays a huge role in many biological processes.

You know how you just feel better during summer and your mood is improved overall? That’s likely thanks to D3.

D3 is also connected with helping to support insulin sensitivity, promoting healthy bone metabolism, and enhancing healthy immune system function which are all excellent reasons to include D3 in Activate Xtreme™.* That said, there are several other benefits to be derived from it.

D3 exerts a POSITIVE effect on androgens and estrogens

D3 levels have been definitively correlated with androgen levels in men. Recent research has suggested that men with higher D3 levels have more circulating testosterone and less SHBG.* With people receiving less sunshine during winter months, especially considering that these are typically “bulking season”, this is not a situation you want your internal environment to be in.

With regards to estrogen support, D3 has also been suggested to exhibit estrogen modulating action. Unlike a direct inhibition of the aromatase enzyme like pZole® exerts, D3 has been surmised to reduce aromatase via two distinct pathways.* Firstly by directly suppressing its transcription at the gene level (i.e. reducing how much of it is produced by the body), and secondly by suppressing cyclooxygenase-2 (COX-2).* This latter effect reduces levels of prostaglandins including prostaglandin E2 (PGE2) which is a major stimulator of aromatase creation. *

D3, IGF-1 and muscular fortification*

D3 also has slightly more direct effects on the support of muscle growth, including a correlation with IGF-1 (Insulin-like Growth Factor-1) levels.* So called because of its structural similarity to insulin, IGF-1 is the means by which GH mediates its anabolic effects in the body. A deficiency in D3 has been suggested to be directly linked to low levels of IGF-1. There also exists a more direct way in which D3 effects muscle cells, through something called the Vitamin D Receptor (VDR). Calcitriol binds to this receptor, activating second messenger systems and influences calcium and phospholipid metabolism. These messenger systems are crucial for muscle repair and development, so much so that mice bred without the VDR have serious growth issues, muscle impairment and poor physical performance. In studies looking into D3 deficiency in HUMANS have found cases of myopathy (muscle weakness) and balance impairment.* Some cases of deficiency have been reversed via daily supplemental D3, which has been suggested to support an increase in performance ability over longer periods.*

D3 and Body Composition*

D3 also plays a role in total body composition. Not only can it have a positive effect on muscle balance, it also has a correlation with body fat levels.* Calcitriol increases calcium uptake in cells which has been suggested to have an association with a reduction in fat cell content.* This is believed to be due, in part, to the effect this calcium influx has on 11beta-Hydroxysteroid Dehydrogenase-1 (11b-HSD1). 11b-HSD1 is the enzyme that converts the inactive cortisone to the active Cortisol. In fat cells, 11b-HSD1 INCREASES fat cell content. By regulating this enzyme, the increased calcium uptake may help support loss of fat in the cells that predominantly express 11b-HSD1. This is also one of the reasons that makes Lean Xtreme™ such a fantastic fat loss support tool!*

In fact, the effect of adequate D3 intake is so pronounced that in humans it may help make dieting easier, with subjects responding better to lower calorie intakes during dieting, leading to more fat loss than those without sufficient D3!* So whether you’re aiming for a lean bulk, or dieting down, Activate Xtreme™ may just be the perfect choice.*

With new studies being released at a rapid rate, there appears to be no end in sight for the benefits of D3.

PROVEN results…

So just how effective is Activate Xtreme™? We conducted an in-house pilot study involving a small group of four participants who used Activate Xtreme™ for four weeks with no other dietary supplements. They followed their usual well-regimented diet and training program and had blood work taken by professional doctors which was then assayed by independent laboratories. On average, tester’s TOTAL testosterone increased by 105%, and their FREE testosterone jumped 136%!! Estrogen was controlled perfectly, with no increases and an average decline of 8.1%.*

 

And Activate Xtreme™ can last ALL DAY LONG!

Thanks to something new and exciting we call Extended Release Technology™! ERT was introduced by DS to ensure that these effects are felt all day long, furnishing your body withthe ideal anabolic environment for building mass!*

Through the powerful combinations of the ingredients found in Activate Xtreme™ you can expect added support for rock hard muscle, increases in strength, high levels of testosterone, and estrogen control.*

So what are you waiting for?

 

CoreTest®, Divanil®, LevoTest®, and Triazole® are registered trademarks of Driven Sports, Inc. All rights reserved. ∆ Awarded on 3/17/11. For references please see the Activate Xtreme™ product FAQ. *These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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